Pain

Recent articles

Research image of neurons in the rostral anterior cingulate cortex (right, in green) sending signals to cells in the pontine nucleus (left, in yellow) to quell pain.

Cerebellar circuit may convert expected pain relief into real thing

The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.

By Angie Voyles Askham
24 July 2024 | 6 min read

Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation

Two new devices take experimenter variation out of the equation, the lead investigators say.

By Calli McMurray
15 May 2024 | 0 min watch

The question of regeneration—an excerpt from ‘Periphery: How Your Nervous System Predicts and Protects Against Disease’

In his recent book, Moses Chao makes the case that the peripheral nervous system can warn of future illnesses.

By Moses V. Chao
26 April 2024 | 7 min read
Research image of presynapses on sensory neurons in fruit flies.

UBE3A’s link to synaptic pruning bolstered by fly study

Increasing or reducing the levels of the UBE3A gene, which is associated with autism and autism-related syndromes, results in altered patterns of synaptic pruning — a process that snips away brain cell connections.

By Giorgia Guglielmi
28 September 2023 | 5 min read
A hand reaches from above to add a pill to a stack that is resting against the x-axis of a graph.

Going on Trial: Epidiolex for autism; arbaclofen tests; pain monitoring

This month’s issue of Going on Trial takes a sneak peek at some early null results from a small trial of a cannabidiol-based drug for autism, among other recent drug developments.

By Peter Hess
30 May 2023 | 7 min read
Research video of a zebrafish larva (zoomed in on the gut) being given glucose.

On the periphery: Thinking ‘outside the brain’ offers new ideas about autism

Neuronal alterations outside the brain may help to explain a host of the condition’s characteristic traits, including sensory changes, gut problems and motor differences.

By Sarah DeWeerdt
13 April 2023 | 20 min read
Woman is holding her fingers to her forehead in pain.

Pain keeps autistic women and girls home from work, school

More autistic women and girls report daily pain than do men and boys with the condition.

By Jaclyn Jeffrey-Wilensky
4 May 2021 | 3 min read
Young woman during birth.

Epidurals linked to slightly higher autism odds, but connection is unclear

Women who receive epidural anesthesia during labor have an elevated chance of having a child with autism, a new study has found. But it is too soon for doctors to recommend against epidurals, experts say.

By Peter Hess
13 October 2020 | 6 min read
human figure outline with various parts drawn in, showing pain

Autistic children disproportionately affected by chronic pain

Children with autism are about twice as likely as their typical peers to experience chronic or repeated pain.

By Jaclyn Jeffrey-Wilensky
13 November 2019 | 3 min read

Explore more from The Transmitter

Illustration of two neon-toned sets of concentric circles overlapping, with bright spots where they intersect.

Are Brains and AI Converging?—an excerpt from ‘ChatGPT and the Future of AI: The Deep Language Revolution’

In his new book, to be published next week, computational neuroscience pioneer Sejnowski tackles debates about AI’s capacity to mirror cognitive processes.

By Terrence Sejnowski
21 October 2024 | 12 min read

New tissue-clearing techniques let microscopes peer deeper into living brains

Washing mouse brain tissue with a blood protein or complex sugar can illuminate cells 550 micrometers into the cortex without compromising its normal physiology.

By Calli McMurray
18 October 2024 | 0 min watch
A younger looking set of hands holds an older looking set of hands.

New catalog charts familial ties from autism to 90 other conditions

The research tool reveals associations stretching across three generations.

By Charles Q. Choi
17 October 2024 | 4 min read